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Image Search Results
Journal: bioRxiv
Article Title: Viral Microglia Reprogramming Clears Oligomeric Neurotoxic Debris
doi: 10.64898/2026.04.06.716590
Figure Lengend Snippet: Microglia phagocytic activity and antigen cross presentation triggered by treatment with mock, poly(I:C), recombinant IFN γ , and PVSRIPO. The phagocytosis/cross presentation assay template with microglia exposure to B16 OVA , described in , was repeated with juxtaposing PVSRIPO to mock, (transfected) poly(I:C), and recombinant IFNγ. Phagocytosis of CD11b + -bead-isolated, hCD155 -tg mouse microglia was determined by flow cytometry analyses of CT-label (A , C) ; antigen cross presentation was tested by flow cytometry for H2Kb:SIINFEKL complexes (B , C) ; cells were tested 0h, 24h, 48h and 72h post treatment; flow cytometry histograms for phagocytosis/cross presentation at 48h and 72h post treatment are shown (C) . (A , B) Data were analyzed by Shapiro-Wilk test and 2-way ANOVA with multiple comparisons.
Article Snippet: Microglia were plated at 70% confluency and infected with PVSRIPO (MOI 10) or mock (DMEM), recombinant mouse IFNγ (200 U/ml; R&D Systems, #485-MI), or poly(
Techniques: Activity Assay, Recombinant, Transfection, Isolation, Flow Cytometry